Criticality of ADME studies in Drug Discovery and Development
One of the critical functions to ensure success at the late stages of drug development are the optimal pharmacokinetic properties of candidate drugs and prevention of related adverse events or toxicities. That is why it is crucial that the absorption, metabolism, distribution and excretion characteristics of compounds are profiled in the early stages of drug discovery to avoid attrition at the later stages of development.
Eurofins Advinus offers the following ADME assays in the hit-to-lead and lead optimization phases to acquire accurate and detailed information on the physicochemical, metabolism and potential drug-drug interaction and distribution properties of the candidate drugs.
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