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                        | Toxicology studies (GLP) 
	Reproduction studies (GLP)Single dose toxicity study in most relevant species (mice/rats/dogs or mini pig)Repeat dose toxicity study with recovery & immunogenicity (mice/rats/rabbits/dogs or mini pig)Local tolerance study in rabbitsJuvenile toxicity studies in rodents 
	Fertility and early embryonic development to implantation (SEG-I) in ratsPrenatal developmental study (SEG-II) in rats and rabbitsPeri-natal and post-natal developmental study (SEG-III) in rats |  |