From Concept to Proof of Concept info@advinus.com   

Equipment Available

  • HPLCs with UV, PDA/DAD, Fluorescence, Refractive Index and Radiochemical (β-RAM) Detector.
  • LC-MS/MS
  • GCs with FID, NPD and ECD Detectors
  • Headspace GC
  • GC-MS
  • Preparatory HPLCs
  • FTIR
  • UV/VIS Spectrophotometers
  • NMR – 400 MHz
  • Biological Oxidizer
  • Radiation Monitor & Radiation Survey Meter
  • Suntest apparatus (for aqueous photolysis study)
  • Liquid Scintillation Counters (LSC)
  • Buchi Syncore Sample Concentrator
  • Explosives and ignition test apparatus

In vitro ADME studies

  • Microplate reader
  • Microplate washer
  • Microplate shaker

In vivo ADME Studies in rodents

  • Metabolic cages equipped with CO2 traps for 14C elimination in expired air
  • Scintillation Counter
  • Radioflow detectors (InUS)
  • Sample Oxidizers

CMC Development (kilo-lab, pilot-plant and clean room)

  • High Performance Liquid Chromatographs (HPLC)
  • Liquid Chromatograph with tandem mass spectrometric detectors (LC-MS/MS)
  • Gas Chromatographs (GC)
  • Preparative HPLC
  • FTIR
  • NMR – 400 MHz
  • Polarimeter
  • Photo stability chamber
  • Stability chambers
  • Karl-Fisher auto-Titrator
  • Glass lined Reactors        250 L – 630 L
  • SS reactors          200 L – 500 L
  • All glass reactor (AGRs) 20 L – 200L
  • Centrifuge (24 inch)        10 Kg – 45 kg
  • Nutsche Filter (SS)           NA
  • Tray Dryer           12 trays
  • Vacuum tray dryers        12 trays
  • Multi mill             50 kg/h
  • Sifter     Up to 20 kg/h
  • Blender                65 L
  • Rotary evaporators         20 L – 50 L
  • Micron Filter      10” Length
  • SS Autoclave      50 ml – 2 L
  • Parr Hydrogenator          500 ml
  • Reaction Calorimeter     1 L
  • Advia 2120 Hematology System – Bayer
  • Automatic Tissue Processor-I
  • CASA (Computer Aided Sperm Analyser) TOX IVOS Analyzer
  • CO2 Incubator
  • Cold Plate EG1150C
  • Columbus Instruments or Bioseb grip strength meter
  • Crusinart Burr Mill
  • Cryostat
  • Dimension RxL Max Clinical Chemistry System
  • ELISA Microplate Reader 680
  • ELISA Microplate Washer
  • Embedding Station
  • Emka Head out Plethysomograph
  • Measurement of Motor activity using Opto-Varimex 4
  • Particle Size Analyser
  • Incubators (CO2 Incubator)
  • Pulverizer
  • Roche/Hitachi 902 Automatic Analyser
  • Multi-mode detectors  – MicroBeta Trilux, Microbeta II, PE EnSpire, PE EnVision, Tecan Safire2
  • FlexStation III (2 units) , Epic
  • Automated workstations – PE Janus, Tecan Evo Freedom
  • Cell  & Bacterial Culture Setup  – Thermo, NuAire Molecular Devices
  • Flow Cytometer – GUAVA EasyCyte Mini
  • Gel Documentation Unit –  Syngene G BOX – HR
  • Rat and mouse telemetry –  DSI
  • Multichannel Data Recording –  AD Instruments, Australia
  • Oxylet –  PanLab-Harvard
  • Drinking and Feed Monitoring  – TSE, Germany
  • Invasive measurement of airway resistance –  Buxco
  • Whole body Plethysmography – Buxco
  • Grip strength meter – Columbus
  • Bioseb TST apparatus  – Bioseb
  • Multi-analyte detection – Lincoplex, Linco
  • Stereotaxic apparatus – Inco
  • Automated refrigeration – Tecniplast
  • Flow meter  – Trasonic
  • Plethysmometer, Rotarod, Analgesiometer, Rectal thermometers
  • LCMS,
  • NMR (400 MHz),
  • HPLCs
  • Mass Guided Purification System: Agilent / 1200 Series, LC / MSD VL
  • Sample Concentrator/ Solvent Evaporator: Thermo/Explorer
  • Freeze Dryer : Thermo / Modulyo