Regulatory toxicology expertise for agrochemicals & industrial chemicals is offered through a partner laboratory, Adgyl Lifesciences.
Eurofins Advinus, in collaboration with its trusted partner laboratory Adgyl Lifesciences, offers comprehensive GLP-compliant toxicology services to support the regulatory registration of crop protection agents and industrial chemicals. With over 30 years of industry leadership, we enable our clients to meet the regulatory requirements of agencies such as US EPA, EMA, MHRA, REACH, CIB (India), and others worldwide.
Through Adgyl Lifesciences, more than 7,000 GLP studies have been successfully conducted, covering the full spectrum of toxicology required for agrochemical product approval.
The testing facility operated via Adgyl Lifesciences is accredited by BfR, AAALAC International, USFDA, CCSEA, and Indian GLP authorities, ensuring adherence to the highest global standards.
Toxicology Service Offerings
1. Genetic Toxicology (In Vitro & In Vivo)
- Ames Test (Bacterial Reverse Mutation Assay)
- In Vitro Chromosomal Aberration (CHO Cells)
- Gene Mutation Assays (Hprt and TK Genes)
- In Vitro Mammalian Micronucleus Test
- In Vivo Micronucleus Test (Rodent Models)
2. General Toxicology Studies (In Vivo)
- Acute Toxicity – “6-Pack” Studies: Oral, Dermal, Inhalation, Eye & Skin Irritation, Skin Sensitization
- Sub-chronic & Chronic Toxicity
- 28-day and 90-day repeat dose (Rodents & Non-Rodents)
- 6–12 month long-term studies
- Carcinogenicity Studies
- 58+ executed; extensive historical data for Wistar, Sprague Dawley rats & Swiss Albino mice
- Transgenic mouse model (Tg.rasH2) also available
- Reproductive & Developmental Toxicology
- Segment II (Rats & Rabbits)
- One-, Two-, and Three-Generation Studies
- Extended One-Generation Reproduction Study (EOGRTS)
- Developmental Neurotoxicity Studies in Rats
3. Specialized Studies
- Local Lymph Node Assay (LLNA) – OECD 429 compliant
- SEND-Compliant Data Files for USFDA regulatory submission
- Peer-reviewed Pathology Reports by certified global experts
Routes of Administration
Flexible administration routes offered, tailored to study requirements:
- Oral (gavage, dietary, drinking water)
- Dermal
- Inhalation
- Ocular
Innovation and Excellence Delivered by Adgyl Lifesciences
- India’s first GLP-certified lab (since 1992)
- AAALAC-accredited vivarium with 140+ rooms, among the largest in South Asia
- 35+ Study Directors with an average of 15+ years of experience
- 9 DABT-certified toxicologists
- Dedicated Quality Assurance Unit (QAU)
- Digital Pathology & Advanced Data Analytics
- Robust historical control datasets for key species and study types
Frequently Asked Questions (FAQs)
What toxicology studies are needed for crop protection registration?
A typical regulatory package includes genetic, acute, sub-chronic, chronic, reproductive, developmental, and carcinogenicity studies. We help tailor this based on the regulatory jurisdiction.
Are these studies compliant with OECD and global guidelines?
Yes. All studies—conducted at Adgyl Lifesciences—follow OECD GLP standards and meet requirements of US EPA, EMA, WHO, JMAFF, DCGI, and other regulatory authorities.
How experienced is your team in handling agrochemical submissions?
Our team includes 35+ study directors and 9 DABT-certified toxicologists, with deep experience in conducting and submitting studies to international regulatory bodies.
Can you provide SEND-format data?
Absolutely. Our systems are fully capable of producing SEND-compliant datasets for seamless submission to US FDA and other global authorities.
How do I initiate a study?
Contact us via our website or email. Our scientific advisors will review your project scope and share a tailored study design aligned with your regulatory objectives.
Let’s Move Your Program Forward
Contact Us to discuss your study needs today.